fever: 40.5 to 42 degrees celsius; fatigue; disturbed menstrual cycle, more periods; more pain around menstruation; disturbed menstrual cycle, more menstrual periods + more intense menstruation; more intense menstruation; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority-web. the reporter is the patient. regulatory number: nl-lrb-00733354 (ra). a 16 year-old female patient received bnt162b2 (comirnaty), administration date 30aug2021 (lot number: unknown) as dose 2, single for covid-19 immunisation. relevant medical history included: "suspected covid-19", start date: 16mar2020 (unspecified if ongoing), notes: disease symptoms: quite. the patient's concomitant medications were not reported. vaccination history included: comirnaty (1st dose, 0.3 ml), administration date: 09aug2021, for covid-19 immunisation, reaction(s): "menstrual cycle shortened"; comirnaty (1st dose, 0.3 ml), administration date: 09aug2021, for covid-19 immunisation, reaction(s): "menorrhagia". the following information was reported: hyperpyrexia (medically significant) with onset 31aug2021, outcome "recovered" (02sep2021), described as "fever: 40.5 to 42 degrees celsius"; fatigue (non-serious) with onset 31aug2021, outcome "recovered" (02sep2021), described as "fatigue"; polymenorrhoea (non-serious) with onset 30aug2021, outcome "not recovered", described as "disturbed menstrual cycle, more periods"; dysmenorrhoea (non-serious) with onset 30aug2021, outcome "not recovered", described as "more pain around menstruation"; condition aggravated (non-serious) with onset 30aug2021, outcome "not recovered", described as "disturbed menstrual cycle, more menstrual periods + more intense menstruation"; heavy menstrual bleeding (non-serious) with onset 30aug2021, outcome "not recovered", described as "more intense menstruation". the events "fever: 40.5 to 42 degrees celsius", "fatigue", "disturbed menstrual cycle, more periods", "more pain around menstruation", "disturbed menstrual cycle, more menstrual periods + more intense menstruation" and "more intense menstruation" were evaluated at the physician office visit. the patient underwent the following laboratory tests and procedures: body temperature: 40.5 to 42, notes: fever. reporter comment: summary: past drug therapy biontech/pfizer vaccine (comirnaty): yes. additional information adr. previous covid-19 infection: disease symptoms: quite. diagnostic procedures: no, the doctor said, we cant do anything with that. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected.; reporter's comments: summary: past drug therapy biontech/pfizer vaccine (comirnaty): yes additional information adr. previous covid-19 infection: disease symptoms: quite diagnostic procedures: no, the doctor said, we cant do anything with that.; sender's comments: linked report(s) : nl-pfizer inc-202200295492 same patient, different dose, different events