heavy menstrual bleeding; chills; headache; fever: 40.5 to 42 degrees celsius; malaise; myalgia; generalized joint pain; fatigue; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority-web. regulatory number: nl-lrb-00736544 (ra). a 26 year-old female patient received bnt162b2 (comirnaty) (batch/lot number: unknown) as dose 1, single for covid-19 immunisation. relevant medical history included: "covid-19", start date: 03aug2021 (unspecified if ongoing). the patient's concomitant medications were not reported. the following information was reported: hyperpyrexia (medically significant) with onset 04nov2021, outcome "recovered" (06nov2021), described as "fever: 40.5 to 42 degrees celsius"; malaise (non-serious) with onset 03nov2021, outcome "recovered" (06nov2021), described as "malaise"; myalgia (non-serious) with onset 03nov2021, outcome "recovered" (06nov2021), described as "myalgia"; chills (non-serious) with onset 05nov2021, outcome "recovered" (06nov2021), described as "chills"; heavy menstrual bleeding (non-serious) with onset 20nov2021, outcome "not recovered", described as "heavy menstrual bleeding"; arthralgia (non-serious) with onset 03nov2021, outcome "recovered" (06nov2021), described as "generalized joint pain"; fatigue (non-serious) with onset 03nov2021, outcome "recovered" (06nov2021), described as "fatigue"; headache (non-serious) with onset 04nov2021, outcome "recovered" (06nov2021), described as "headache". the patient underwent the following laboratory tests and procedures: body temperature: (04nov2021) 40.5 to 42, notes: fever; sars-cov-2 test: (03aug2021) positive. reporter comment: biontech/pfizer vaccine (comirnaty) past drug therapy biontech/pfizer vaccine (comirnaty): no heavy menstruation after vaccination additional information adr: every 4 weeks it come backs more heavily than previously (privacy) number available: yes covid19 previous covid-19 infection: disease symptoms: quite no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected