after 12 years of menopause, menstruating again on 01aug2021; this is a spontaneous report received from a contactable reporter (consumer or other non hcp) from the ra, regulatory number: nl-lrb-00736729 (ra). a 54 year-old female patient received bnt162b2 (comirnaty, 0.3 ml), administration date 16jul2021 (lot number: fe7010) as dose 2, 0.3 ml single for covid-19 immunisation. relevant medical history included: "early menopause" (unspecified if ongoing), notes: due to chemotherapy in 2003; "chemotherapy", start date: 2003 (unspecified if ongoing). the patient's concomitant medications were not reported. vaccination history included: comirnaty (dose 1, 0.3ml), administration date: 05jun2021, for covid-19 immunisation, reaction: "no adverse event". the patient had no previous covid-19 infection. the following information was reported: postmenopausal haemorrhage (medically significant) with onset 01aug2021, outcome "not recovered", described as "after 12 years of menopause, menstruating again on 01aug2021". the patient underwent the following laboratory tests and procedures: tissue sampling: (10sep2021) unknown results, notes: further examination indicated; uterine endoscopy: (01sep2021) unknown results, notes: further examination indicated; hysteroscopy: (10jan2022) unknown results; pap smear: (10aug2021) unknown results. therapeutic measures were taken as a result of postmenopausal haemorrhage. reporter comment: past drug therapy biontech/pfizer vaccine (comirnaty): yes. adrs: no date: 05jun2021. previous covid-19 infection: no. no follow-up attempts are possible. no further information is expected.; reporter's comments: past drug therapy biontech/pfizer vaccine (comirnaty): yes. adrs: no date: 05jun2021. previous covid-19 infection: no

test date: 20210910; test name: tissue sampling; result unstructured data: test result:unknown results; comments: further examination indicated; test date: 20210901; test name: uterine endoscopy; result unstructured data: test result:unknown results; comments: further examination indicated; test date: 20220110; test name: hysteroscopy; result unstructured data: test result:unknown results; test date: 20210810; test name: pap smear; result unstructured data: test result:unknown results

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