vaccination failure; covid-19; fatigue; abdominal pain; constipation; irregular menstrual cycle; malaise; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority -web. regulatory number: nl-lrb-00737231. a 20 year-old female patient received bnt162b2 (comirnaty), administration date 09aug2021 (lot number: unknown) as dose 2, single for covid-19 immunisation. relevant medical history included: "covid-19", start date: 16dec2021 (unspecified if ongoing), notes: at 23:00:00. the patient's concomitant medications were not reported. vaccination history included: comirnaty (dose 1, single, 0.3ml, batch/lot number: unknown.), administration date: 04jul2021, for covid-19 immunisation. the following information was reported: vaccination failure (medically significant) with onset 16dec2021, outcome "unknown", described as "vaccination failure"; covid-19 (medically significant) with onset 16dec2021, outcome "unknown", described as "covid-19"; malaise (non-serious) with onset 10aug2021, outcome "recovering", described as "malaise"; constipation (non-serious) with onset 06dec2021, outcome "not recovered", described as "constipation"; menstruation irregular (non-serious) with onset 06dec2021, outcome "not recovered", described as "irregular menstrual cycle"; abdominal pain (non-serious) with onset 07dec2021, outcome "recovering", described as "abdominal pain"; fatigue (non-serious) with onset 10dec2021, outcome "not recovered", described as "fatigue". the patient underwent the following laboratory tests and procedures: sars-cov-2 test positive: (16dec2021) positive, notes: at 23:00:00. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected