left breast lymph node swelling; menstrual cycle interrupted; this is a spontaneous report received from a contactable reporter(s) (physician) from the regulatory authority-web. regulatory number: gr-greof-202200855 (ra). a 38 year-old female patient received bnt162b2 (comirnaty), administration date 09aug2021 (batch/lot number: unknown) at the age of 38 years as dose 2, single for covid-19 immunisation. the patient had no relevant medical history. there were no concomitant medications. vaccination history included: covid-19 vaccine (dose 1), for covid-19 immunisation. the following information was reported: menstrual disorder (medically significant) with onset 09aug2021, outcome "recovered" (21dec2021), described as "menstrual cycle interrupted"; lymphadenopathy (non-serious), outcome "unknown", described as "left breast lymph node swelling". additional information: no alcohol, no smoker, no medical history, no other drugs. the patient presented menstrual cycle interruption, until then she had a 28 days cycle. also, she presented left breast lymph node swelling. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected